Searchable abstracts of presentations at key conferences in endocrinology

ea0037ep1337 | Clinical Cases–Thyroid/Other | ECE2015

Recurrent severe symptomatic hyponatraemia induced by low-dose oral cyclophosphamide in a patient with ANA-related vasculitis

Dineen Rosemary , Pazderska Agnieszka , Mullan Ronan , Gibney James , Sherlock Mark

Cyclophosphamide is an alkylating agent used in the treatment of malignant and autoimmune diseases. Severe hyponatraemia is a serious electrolyte disorder with life threatening neurological sequelae. We report a case of recurrent severe, symptomatic hyponatraemia that developed in a 61 year old female with systemic vasculitis and Sjogrens syndrome following low-dose cyclophosphamide.Case report: A 61 year old lady, with ANA positive systemic vasculitis p...